Oncogenicity of SV40 DNA in the Syrian Hamster

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Studies on transformation of Syrian hamster cells by simian virus 40 (SV40): acquisition of oncogenicity by virus-exposed cells apparently unassociated with the viral genome.

During a study of the capacity of Syrian hamster cells derived from various organs to transform in vitro after exposure to simian virus 40 (SV40), it was found that cells from lung and liver responded differently compared to those from certain other organs. The most significant difference was the apparent absence of the viral genome in lung and liver cultures that eventually underwent transform...

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 1977

ISSN: 0022-1317,1465-2099

DOI: 10.1099/0022-1317-37-3-635